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1.
Psychol Med ; 53(15): 7214-7221, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37039122

RESUMO

BACKGROUND: This study tested whether the dissonance-based Body Project eating disorder prevention program reduced onset of subthreshold/threshold anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD) over long-term follow-up. METHODS: Data were combined from three prevention trials that targeted young women at high-risk for eating disorders (N = 1092; M age = 19.3). Participants were randomized to Body Project groups led by peer educators or expressive writing/educational controls and completed masked diagnostic interviews over 2- to 4-year follow-ups. Logistic regressions tested whether onset of each eating disorder over follow-up differed between Body Project and control participants. RESULTS: Peer-led Body Project groups produced a 46% reduction in onset of subthreshold/threshold BN and a 62% reduction in onset of PD relative to controls over follow-up. Rates of onset of subthreshold/threshold AN and BED did not significantly differ between peer-led Body Project participants and control participants. CONCLUSIONS: Results support the dissemination of the peer-led Body Project for reducing future onset of BN and PD. This study and recent research suggest that thin-ideal internalization, the risk factor for eating disorders targeted in the Body Project, may be more relevant for predicting onset of BN and PD compared to AN and BED. Findings support the development of a version of the Body Project aimed to reduce risk factors that have predicted future onset of all four types of eating disorders (e.g. overvaluation of weight/shape, fear of weight gain), which may more effectively prevent all eating disorder types.


Assuntos
Anorexia Nervosa , Transtorno da Compulsão Alimentar , Bulimia Nervosa , Transtornos da Alimentação e da Ingestão de Alimentos , Feminino , Humanos , Adulto Jovem , Adulto , Imagem Corporal , Transtornos da Alimentação e da Ingestão de Alimentos/prevenção & controle , Bulimia Nervosa/prevenção & controle , Bulimia Nervosa/diagnóstico , Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/diagnóstico , Anorexia Nervosa/prevenção & controle , Anorexia Nervosa/diagnóstico
2.
Eat Disord ; 31(2): 128-138, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36794482

RESUMO

A broad array of important and diverse studies surrounding the treatment of eating disorders were published in Eating Disorders: The Journal of Treatment & Prevention in 2022. Novel interventions such as neurosurgical and neuromodulatory treatments were discussed, as evidence continues to mount around their potential utility in treating eating disorders, in particular namely anorexia nervosa. Important pragmatic and theoretical developments around feeding and refeeding approaches emerged, and are also discussed. In this review, we carefully review evidence alluding to the potential efficacy of exercise in partially ameliorating binge eating disorder symptomatology, while examining broader evidence underscoring the importance of therapeutically ameliorating compulsive exercise in anorexia nervosa and bulimia nervosa. In addition, we overview evidence relating to the risk and sequelae associated with premature discharge from intensive eating disorder treatment, as well as the efficacy of CBT versus group therapy-based maintenance treatments. Finally, important developments around the use of open versus blind weighing in treatment are assessed. Overall, the articles published in Eating Disorders: The Journal of Treatment & Prevention in 2022 evidence the promise of treatment advances in the field and requires further work to address the development of efficacious treatments to achieve greater outcomes for those with eating disorders.


Assuntos
Anorexia Nervosa , Transtorno da Compulsão Alimentar , Bulimia Nervosa , Terapia Cognitivo-Comportamental , Transtornos da Alimentação e da Ingestão de Alimentos , Humanos , Psicoterapia , Transtornos da Alimentação e da Ingestão de Alimentos/prevenção & controle , Bulimia Nervosa/terapia , Transtorno da Compulsão Alimentar/prevenção & controle
3.
Psychol Med ; 53(4): 1277-1287, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-34247660

RESUMO

BACKGROUND: Existing internet-based prevention and treatment programmes for binge eating are composed of multiple distinct modules that are designed to target a broad range of risk or maintaining factors. Such multi-modular programmes (1) may be unnecessarily long for those who do not require a full course of intervention and (2) make it difficult to distinguish those techniques that are effective from those that are redundant. Since dietary restraint is a well-replicated risk and maintaining factor for binge eating, we developed an internet- and app-based intervention composed solely of cognitive-behavioural techniques designed to modify dietary restraint as a mechanism to target binge eating. We tested the efficacy of this combined selective and indicated prevention programme in 403 participants, most of whom were highly symptomatic (90% reported binge eating once per week). METHOD: Participants were randomly assigned to the internet intervention (n = 201) or an informational control group (n = 202). The primary outcome was objective binge-eating frequency. Secondary outcomes were indices of dietary restraint, shape, weight, and eating concerns, subjective binge eating, disinhibition, and psychological distress. Analyses were intention-to-treat. RESULTS: Intervention participants reported greater reductions in objective binge-eating episodes compared to the control group at post-test (small effect size). Significant effects were also observed on each of the secondary outcomes (small to large effect sizes). Improvements were sustained at 8 week follow-up. CONCLUSIONS: Highly focused digital interventions that target one central risk/maintaining factor may be sufficient to induce meaningful change in core eating disorder symptoms.


Assuntos
Transtorno da Compulsão Alimentar , Bulimia , Terapia Cognitivo-Comportamental , Aplicativos Móveis , Humanos , Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/diagnóstico , Terapia Cognitivo-Comportamental/métodos , Resultado do Tratamento , Bulimia/prevenção & controle , Internet
4.
Arq Bras Cir Dig ; 35: e1659, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35766604

RESUMO

AIM: The use of probiotics as adjuvants in the treatment of eating disorders, known as psychobiotics, has already been investigated as a means of modulating the microbiota-gut-brain axis. This study aimed to assess the effect of probiotic supplementation on binge eating and food addiction in subjects after Roux-en-Y gastric bypass surgery. METHODS: This is a randomized, double-blind, placebo-controlled trial involving 101 patients who received probiotic (Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07) or placebo supplements for 90 days after bariatric surgery, starting on the seventh postoperative day. They were evaluated preoperatively (T0) and postoperatively at 90 days (T1) and 1 year (T2) after surgery. The Yale Food Addiction Scale (YFAS) and Binge Eating Scale (BES) were applied to assess food addiction and binge eating, respectively. RESULTS: Before surgery, one-third of the patients presented with a food addiction and binge eating diagnosis. The number of symptoms of YFAS and the BES score decreased significantly in both groups at T1 compared to T0. However, a significant effect of treatment with probiotics was observed 1 year after surgery (T2). Both the number of symptoms of food addiction and the binge eating score were lower in the probiotic group than in the placebo group (p=0.037 and p=0.030, respectively). CONCLUSION: The use of probiotic supplementation for 90 days in the immediate postoperative period may decrease food addiction symptoms and binge eating score up to 1 year after surgery compared to controls.


Assuntos
Transtorno da Compulsão Alimentar , Bulimia , Dependência de Alimentos , Derivação Gástrica , Probióticos , Transtorno da Compulsão Alimentar/prevenção & controle , Suplementos Nutricionais , Método Duplo-Cego , Dependência de Alimentos/diagnóstico , Humanos , Probióticos/uso terapêutico
5.
Behav Ther ; 52(2): 442-454, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33622512

RESUMO

Approximately 50% of individuals fail to obtain treatment benefits when undergoing cognitive-behavioral therapy (CBT) for binge-eating behaviors, making it necessary to evaluate additional approaches. Cue exposure and response prevention (CERP) is one such approach, although its effectiveness across studies has been inconsistent. This may be due to inconsistent implementation of theoretically based CERP strategies. This possibility has not yet been systematically investigated. To address this gap, this review investigated which CERP strategies have been incorporated into treatment protocols for binge eating, and if the use of certain strategies improves treatment effectiveness. Relevant studies were identified through reference lists, grey literature, and searches of electronic databases using multiple search terms related to CERP and binge eating, which resulted in 18 eligible studies. Most studies were underpowered, many were of low methodological quality, and none of the included studies utilized all of the strategies that have been recommended to optimize CERP. Despite these weaknesses, CERP appeared to reduce the frequency of binge eating in the short and long term. This review underscores the need for higher quality research that utilizes larger samples and uniform outcome measures that are more strongly grounded in theory. Such research would help improve treatment outcomes for binge eating.


Assuntos
Transtorno da Compulsão Alimentar , Terapia Cognitivo-Comportamental , Transtorno da Compulsão Alimentar/prevenção & controle , Sinais (Psicologia) , Comportamento Alimentar , Humanos , Resultado do Tratamento
6.
Eat Behav ; 38: 101408, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32585564

RESUMO

OBJECTIVE: Military adolescent boys report similar levels of disordered-eating as their female counterparts. Yet, interventions for the prevention of full-threshold eating disorders in adolescent boys are lacking. Interpersonal psychotherapy (IPT), an evidenced-based therapy adapted for the prevention of BED and adult obesity, has been studied in adolescent girls, but it is unclear whether IPT might resonate with adolescent boys. METHOD: The current case study elucidates the use of a 12-week IPT group intervention for the prevention of BED and adult obesity in adulthood for an African American adolescent military dependent boy with reported loss-of-control (LOC)-eating, obesity, and elevated mood symptoms. RESULTS: LOC-eating and body mass index metrics decreased immediately post-intervention and further decreased by one-year follow-up. Social functioning scores improved and anxiety and depression scores decreased from baseline to one-year follow-up. In contrast to previous observations among girls, these improvements were evidenced without the teen's explicit acknowledgement of the link between mood and eating behaviors. DISCUSSION: Although the mechanism of change may manifest differently than for girls, adapted IPT may be an effective intervention strategy for adolescent boys with LOC-eating and obesity who endorse elevated mood symptoms.


Assuntos
Transtorno da Compulsão Alimentar , Militares , Adolescente , Adulto , Negro ou Afro-Americano , Transtorno da Compulsão Alimentar/prevenção & controle , Feminino , Humanos , Psicoterapia Interpessoal , Masculino , Obesidade/prevenção & controle , Psicoterapia
7.
Diabetes Metab Syndr ; 14(4): 289-292, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32289741

RESUMO

AIMS: Binge eating disorder (BED) is the most common eating disorder in the United States and Europe and is associated with obesity and type 2 diabetes (T2D). Presence and severity of BED have been associated with worse metabolic control and greater BMI in T2D patients. Glucagon Like Peptide-1 (GLP1) receptors are present in central nervous system areas involved in appetite regulation and treatment with GLP-1 receptor agonists modulates appetite and reward-related brain areas in humans. We evaluated the effects of treatment with dulaglutide on eating behavior in T2D outpatients with BED. METHODS: This was a pilot open label, prospective controlled study. Inclusion criteria were: Age ≤65, HbA1c between 7.5 and 9% on metformin therapy alone, normal renal function and diagnosis of BED. Patients were randomly assigned to receive either Dulaglutide 1,5 mg/sett or Gliclazide 60 mg for 12 weeks. We evaluated baseline binge eating scale score (BES), weight, BMI, percentage fat mass, HbA1c and their changes after treatment. A multivariate linear regression model was used to verify the association between Δ BES from baseline with Δ Hba1c and variation of anthropometric parameters after treatment. RESULTS: After 12 weeks patients treated with dulaglutide had grater reduction of binge eating behaviour (p < 0.0001), body weight (p < 0,0001), BMI (p < 0.0001), percentage fat mass (p < 0.0001) and HbA1c (p = 0.009) than patients treated with gliclazide. Reduction in BES was associated with reduction in body weight (p < 0.0001) and HbA1c (p = 0.033). CONCLUSION: Dulaglutide treatment reduces binge eating behaviour in T2D patients with BED.


Assuntos
Transtorno da Compulsão Alimentar/prevenção & controle , Biomarcadores/análise , Diabetes Mellitus Tipo 2/tratamento farmacológico , Peptídeos Semelhantes ao Glucagon/análogos & derivados , Hipoglicemiantes/uso terapêutico , Fragmentos Fc das Imunoglobulinas/uso terapêutico , Proteínas Recombinantes de Fusão/uso terapêutico , Idoso , Transtorno da Compulsão Alimentar/complicações , Transtorno da Compulsão Alimentar/patologia , Glicemia/análise , Peso Corporal , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/patologia , Feminino , Seguimentos , Peptídeos Semelhantes ao Glucagon/uso terapêutico , Hemoglobinas Glicadas/análise , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Prognóstico , Estudos Prospectivos
8.
Am Psychol ; 75(2): 189-203, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32052994

RESUMO

Although binge-eating disorder may manifest in childhood, a significantly larger proportion of youth report episodes involving a loss of control while eating, the hallmark feature of binge eating that predicts excess weight gain and obesity. Adults with binge-eating disorder often report that symptoms emerged during childhood or adolescence, suggesting that a developmental perspective of binge eating may be warranted. Thus, loss of control eating may be a marker of prodromal binge-eating disorder among certain susceptible youth. The present article offers a broad developmental framework of binge-eating disorder and proposes areas of future research to determine which youths with loss of control eating are at risk for persistent and exacerbated behavior that may develop into binge-eating disorder and adult obesity. To this end, this article provides an overview of loss of control eating in childhood and adolescence, including its characterization, etiology, and clinical significance, with a particular focus on associations with metabolic risk, weight gain, and obesity. A conceptual model is proposed to further elucidate the mechanisms that may play a role in determining which youths with loss of control are at greatest risk for binge-eating disorder and obesity. Ways in which treatments for adult binge-eating disorder may inform approaches to reduce loss of control eating and prevent excess weight gain in youth are discussed. (PsycINFO Database Record (c) 2020 APA, all rights reserved).


Assuntos
Transtorno da Compulsão Alimentar/psicologia , Obesidade Pediátrica/psicologia , Adolescente , Terapia Comportamental , Transtorno da Compulsão Alimentar/complicações , Transtorno da Compulsão Alimentar/prevenção & controle , Criança , Humanos , Obesidade Pediátrica/complicações , Obesidade Pediátrica/prevenção & controle , Fatores de Risco
9.
Eat Behav ; 34: 101307, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31220739

RESUMO

BACKGROUND: Body dissatisfaction and dietary restraint are established risk factors for eating disorders and are also prevalent in individuals who are overweight and obese. Studies have shown that online prevention programs can lower these risk factors. The aim of this feasibility pilot study was to estimate effects of a 12-week online health promotion and eating disorder prevention program in a sample of women with overweight or obesity, but without binge eating. METHODS: The program was evaluated in an uncontrolled pre-post-follow-upstudy over 12 months. Outcome measures were eating disorder related cognitions and attitudes. Participants were recruited via flyers, online posts, press releases, and mailings through cooperating health insurances. RESULTS: 371 women who completed the screening met the inclusion criteria. 323 women took part in the baseline assessment and were granted access to the intervention. 50 women completed all sessions. An intention-to-treat analysis showed significant and long-term reductions in weight and shape concerns, restrictive eating and increases in life satisfaction and self-esteem (d = 0.31-0.86), and a short-term increase in fruit and vegetable consumption (d = 0.70). CONCLUSION: everyBody fit seems a feasible program for improving body image and reducing disordered eating in overweight and obese women, with medium to large effects on various outcomes. The efficacy of the intervention needs to be established in a randomized controlled trial.


Assuntos
Transtorno da Compulsão Alimentar/prevenção & controle , Imagem Corporal/psicologia , Bulimia/prevenção & controle , Promoção da Saúde/métodos , Obesidade/prevenção & controle , Obesidade/psicologia , Adulto , Idoso , Peso Corporal , Dieta , Estudos de Viabilidade , Feminino , Humanos , Internet , Pessoa de Meia-Idade , Projetos Piloto , Autoimagem , Verduras , Adulto Jovem
10.
Psychiatr Clin North Am ; 42(2): 309-318, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31046932

RESUMO

Thirteen percent of girls and women experience an eating disorder, yet most do not receive treatment. Thus, broad implementation of eating disorder prevention programs that reduce eating disorder symptoms and future eating disorder onset is a critical priority. This article (1) reviews risk factors that have been shown to predict future onset of eating disorders, because this should guide the content of prevention programs and high-risk subgroups to target with selective prevention programs; (2) reviews the evidence base for eating disorder prevention programs that have reduced eating disorder symptoms or future onset of eating disorders; and (3) discusses directions for future research.


Assuntos
Anorexia Nervosa/epidemiologia , Anorexia Nervosa/prevenção & controle , Transtorno da Compulsão Alimentar/epidemiologia , Transtorno da Compulsão Alimentar/prevenção & controle , Bulimia Nervosa/prevenção & controle , Imagem Corporal , Bulimia Nervosa/epidemiologia , Medicina Baseada em Evidências , Humanos , Fatores de Risco
11.
Appetite ; 138: 184-189, 2019 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-30940610

RESUMO

Binge eating disorder (BED) is characterized, in part, by recurrent episodes of eating large quantities of food in a short period of time. Repetitive binge episodes are a common pattern of consumption during the early stages of substance abuse, and it has been proposed that binge patterns of consumption might favor the transition to BED and "food addiction". Therefore, it is of paramount importance to provide new behavioral strategies that protect vulnerable binge-prone individuals from transitioning to BED and food addiction. Recently, we showed protective and therapeutic benefits of environmental enrichment (EE) on binge-like intake of ethanol in C57BL/6J mice, in agreement with previous evidence showing EE modulation of drug intake, drug relapse and drug reward. In the present study, adolescent mice reared under EE conditions were evaluated for binge-like consumption of sucrose during adulthood in a long-term drinking in the dark (DID) procedure that effectively models binge consumption in humans. Additionally, we tested binge-like intake in adults reared under standard conditions (SE) with long-term exposure to sucrose DID and the effects on sucrose DID of switching from SE to EE conditions. We report here, for the first time, that early EE exposure protects mice from binge-like excessive sucrose intake during adulthood. Ongoing binge-like high sucrose intake in SE-reared mice was also significantly reduced when switched to EE conditions. The present observations suggest that EE exposure might be a promising tool for preventing repetitive binge-like sucrose consumption from transitioning to BED and food addiction.


Assuntos
Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/terapia , Meio Ambiente , Jogos e Brinquedos/psicologia , Recompensa , Sacarose/administração & dosagem , Animais , Comportamento Animal , Transtorno da Compulsão Alimentar/psicologia , Modelos Animais de Doenças , Masculino , Camundongos , Camundongos Endogâmicos C57BL
12.
Eval Program Plann ; 69: 33-42, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29665478

RESUMO

Evidence-based obesity reduction programs in the Pacific are scarce to nonexistent. Using a community-based participatory research model (CBPR) we developed a collaboration between our university and a small Pacific Island nation. We established an advisory council of local stakeholders and then conducted an extensive needs assessment with youth, parents, professionals, and lay public. Only 9% of participants had tried a weight loss program. There was a strong tendency to engage in binge-eating cycles; difficulty eating healthy during frequent community celebrations with few healthy food options available in general; and limited traditions that involved physical activity. Participants wanted to learn how to increase their physical activity, make healthier food choices, and learn to reward themselves for healthy behaviors. Diets were most frequently high in energy or protein foods, followed by starch, sugary and fried foods; they ate vegetables and fruits least often. Together, our team then created the culturally relevant Fit Kit Palau©. We highlight lessons learned including how to determine partnerships; manage multiple cultural and geographic barriers; build capacity; and balance program fidelity with responsivity. As the program moves forward, we hope to increase access, engagement, and adherence and provide a model for other PI countries.


Assuntos
Comportamentos Relacionados com a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Promoção da Saúde/métodos , Determinação de Necessidades de Cuidados de Saúde , Obesidade/prevenção & controle , Obesidade/psicologia , Adolescente , Adulto , Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/psicologia , Pesquisa Participativa Baseada na Comunidade , Relações Comunidade-Instituição , Dieta , Exercício Físico , Feminino , Humanos , Masculino , Micronésia , Pessoa de Meia-Idade , Desenvolvimento de Programas , Estresse Psicológico , Universidades , Adulto Jovem
13.
J Addict Nurs ; 29(1): 32-42, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29505459

RESUMO

Binge eating disorder, food addiction, and dysregulated overeating are common among people with severe obesity and prevalent among bariatric surgery populations. These problematic eating habits share commonalities with other addictions. Effective, holistic self-management is needed to promote long-term weight loss and psychosocial adjustment among patients who are severely obese who undergo surgery, especially those with clinically remarkable levels of binge eating, food addiction, or dysregulated overeating.This article aims to briefly review binge eating disorder, food addiction, and obesity-as well as issues surrounding surgery for individuals who are severely obese-and introduce the Bariatric Outcomes: Self-management for Sustained Surgical Success (BOSSSS) program. The BOSSSS program is holistic, skill based, and designed to promote weight loss, prevent weight regain, and improve well-being in patients with severe obesity with a history of bariatric surgery.Preliminary survey data suggest that bariatric surgery patients report a lack of skill-based emotional and behavioral support designed to help them over the long term. The BOSSSS program is rooted in self-determination theory, integrating mobile health technology across program components. Self-determination theory-based interventions are personalized and encourage autonomy, competence, and social support among participating patients and providers. The behavioral self-regulation training within BOSSSS is energy balance self-monitoring and titration. Emotional self-regulation is addressed via a specialized version of dialectical behavior skills therapy, emphasizing promotion of coping skills and use of adaptive, healthy substances in immediate environments. The BOSSSS program has been well received by patients and could be implemented by nurses and other health professionals with minimal support.


Assuntos
Transtorno da Compulsão Alimentar/prevenção & controle , Obesidade Mórbida/cirurgia , Complicações Pós-Operatórias/prevenção & controle , Adaptação Psicológica , Cirurgia Bariátrica , Terapia Comportamental , Transtorno da Compulsão Alimentar/enfermagem , Feminino , Humanos , Masculino , Papel do Profissional de Enfermagem , Obesidade Mórbida/reabilitação , Complicações Pós-Operatórias/enfermagem , Autogestão
14.
Cell Metab ; 25(6): 1269-1281.e6, 2017 Jun 06.
Artigo em Inglês | MEDLINE | ID: mdl-28576418

RESUMO

Binge eating (BE) is a common aberrant form of eating behavior, characterized by overconsumption of food in a brief period of time. Recurrent episodes of BE constitute the BE disorder, which mostly affects females and is associated with early-life adversities. Here, we show that corticotropin releasing factor (CRF)-induced prenatal stress (PNS) in late gestation predisposes female offspring to BE-like behavior that coincides with hypomethylation of hypothalamic miR-1a and downstream dysregulation of the melanocortin system through Pax7/Pax3. Moreover, exposing the offspring to a methyl-balanced diet during adolescence prevents the dysregulation and predisposition from being triggered. We demonstrate that gestational programming, per se, will not lead to BE-like behavior, but pre-existing alterations due to prenatal programming are revealed only when challenged during adolescence. We provide experimental evidence for long-term epigenetic abnormalities stemming from PNS in predisposing female offspring to BE disorder as well as a potential non-invasive prevention strategy.


Assuntos
Transtorno da Compulsão Alimentar/prevenção & controle , Dieta , Exposição Materna/prevenção & controle , Efeitos Tardios da Exposição Pré-Natal/prevenção & controle , Estresse Fisiológico , Animais , Transtorno da Compulsão Alimentar/fisiopatologia , Feminino , Camundongos Endogâmicos ICR , Gravidez , Efeitos Tardios da Exposição Pré-Natal/fisiopatologia
15.
Obes Surg ; 27(3): 670-675, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-27491293

RESUMO

OBJECTIVE: This study aimed to determine the feasibility and preliminary efficacy of a post-operative telephone-based cognitive behavioral therapy intervention (Tele-CBT) in improving eating pathology and psychosocial functioning. METHODS: Six-month post-operative bariatric surgery patients (n = 19) received six sessions of Tele-CBT. Study outcome variables included binge eating (BES), emotional eating (EES), depressive symptoms (PHQ-9), and anxiety symptoms (GAD-7). RESULTS: Retention was 73.7 % post-intervention. Tele-CBT resulted in significant reductions in mean difference scores on BES, EES-Total, EES-Anxiety, EES-Anger, PHQ9, and GAD7. Tele-CBT patients experienced a mean weight loss of 8.62 ± 15.02 kg between 6-months post-surgery (pre-Tele-CBT) and 12-months post-surgery. CONCLUSIONS: These preliminary results suggest that post-surgery Tele-CBT is feasible and can improve post-surgery symptoms of psychopathology in this uncontrolled study, supporting the need for a randomized controlled trial.


Assuntos
Terapia Cognitivo-Comportamental/métodos , Obesidade Mórbida/terapia , Telefone , Adulto , Ansiedade/etiologia , Ansiedade/prevenção & controle , Transtornos de Ansiedade/etiologia , Transtornos de Ansiedade/prevenção & controle , Cirurgia Bariátrica/métodos , Transtorno da Compulsão Alimentar/etiologia , Transtorno da Compulsão Alimentar/prevenção & controle , Bulimia/etiologia , Bulimia/prevenção & controle , Terapia Combinada , Depressão/etiologia , Depressão/prevenção & controle , Estudos de Viabilidade , Transtornos da Alimentação e da Ingestão de Alimentos/etiologia , Transtornos da Alimentação e da Ingestão de Alimentos/prevenção & controle , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/psicologia , Obesidade Mórbida/cirurgia , Projetos Piloto , Período Pós-Operatório , Resultado do Tratamento , Adulto Jovem
16.
Neuropsychopharmacology ; 42(7): 1458-1470, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27711047

RESUMO

Compulsive, binge eating of highly palatable food constitutes a core feature of some forms of obesity and eating disorders, as well as of the recently proposed disorder of food addiction. Trace amine-associated receptor 1 (TAAR1) is a highly conserved G-protein-coupled receptor bound by endogenous trace amines. TAAR1 agonists have been shown to reduce multiple behavioral effects of drugs of abuse through their actions on the mesocorticolimbic system. In this study, we hypothesized that TAAR1 may have a role in compulsive, binge-like eating; we tested this hypothesis by assessing the effects of a TAAR1 agonist, RO5256390, in multiple excessive feeding-related behaviors induced by limiting access to a highly palatable diet in rats. Our results show that RO5256390 blocked binge-like eating in rats responding 1 h per day for a highly palatable sugary diet. Consistent with a palatability-selective effect, drug treatment selectively reduced the rate and regularity of palatable food responding, but it did not affect either baseline intake or food restriction-induced overeating of the standard chow diet. Furthermore, RO5256390 fully blocked compulsive-like eating when the palatable diet was offered in an aversive compartment of a light/dark conflict box, and blocked the conditioned rewarding properties of palatable food, as well as palatable food-seeking behavior in a second-order schedule of reinforcement. Drug treatment had no effect on either anxiety-like or depressive-like behavior, and it did not affect control performance in any of the tests. Importantly, rats exposed to palatable food showed decreased TAAR1 levels in the medial prefrontal cortex (mPFC), and RO5256390 microinfused into the infralimbic, but not prelimbic, subregion of the mPFC-reduced binge-like eating. Altogether, these results provide evidence for TAAR1 agonism as a novel pharmacological treatment for compulsive, binge eating.


Assuntos
Transtorno da Compulsão Alimentar/metabolismo , Transtorno da Compulsão Alimentar/prevenção & controle , Comportamento Compulsivo/metabolismo , Comportamento Compulsivo/prevenção & controle , Receptores Acoplados a Proteínas G/agonistas , Receptores Acoplados a Proteínas G/metabolismo , Animais , Transtorno da Compulsão Alimentar/psicologia , Comportamento Compulsivo/psicologia , Condicionamento Operante/efeitos dos fármacos , Condicionamento Operante/fisiologia , Comportamento Alimentar/efeitos dos fármacos , Comportamento Alimentar/psicologia , Masculino , Córtex Pré-Frontal/efeitos dos fármacos , Córtex Pré-Frontal/metabolismo , Ratos , Ratos Wistar
17.
Einstein (Sao Paulo) ; 14(2): 235-77, 2016.
Artigo em Inglês, Português | MEDLINE | ID: mdl-27462898

RESUMO

Eating disorders are psychiatric conditions originated from and perpetuated by individual, family and sociocultural factors. The psychosocial approach to treatment and prevention of relapse is crucial. To present an overview of the scientific evidence on effectiveness of psychosocial interventions in treatment of eating disorders. All systematic reviews published by the Cochrane Database of Systematic Reviews - Cochrane Library on the topic were included. Afterwards, as from the least recent date of these reviews (2001), an additional search was conducted at PubMed with sensitive search strategy and with the same keywords used. A total of 101 primary studies and 30 systematic reviews (5 Cochrane systematic reviews), meta-analysis, guidelines or narrative reviews of literature were included. The main outcomes were: symptomatic remission, body image, cognitive distortion, psychiatric comorbidity, psychosocial functioning and patient satisfaction. The cognitive behavioral approach was the most effective treatment, especially for bulimia nervosa, binge eating disorder and the night eating syndrome. For anorexia nervosa, the family approach showed greater effectiveness. Other effective approaches were interpersonal psychotherapy, dialectic behavioral therapy, support therapy and self-help manuals. Moreover, there was an increasing number of preventive and promotional approaches that addressed individual, family and social risk factors, being promising for the development of positive self-image and self-efficacy. Further studies are required to evaluate the impact of multidisciplinary approaches on all eating disorders, as well as the cost-effectiveness of some effective modalities, such as the cognitive behavioral therapy. RESUMO Transtornos alimentares são doenças psiquiátricas originadas de e perpetuadas por fatores individuais, familiares e socioculturais. A abordagem psicossocial é essencial para o tratamento e a prevenção de recaídas. Apresentar uma visão geral das evidências científicas sobre a efetividade das intervenções psicossociais no tratamento de transtornos alimentares. Foram incluídas todas as revisões sistemáticas publicadas no Banco de Dados de Revisões Sistemáticas da Cochrane Library. Posteriormente, a partir da data menos recente destas revisões (2001), realizou-se uma busca adicional no PubMed, com estratégia de busca sensibilizada e com os mesmos descritores utilizados antes. No total, foram incluídos 101 estudos primários e 30 revisões sistemáticas (5 revisões sistemáticas da Cochrane), metanálises, diretrizes ou revisões narrativas da literatura. Os principais desfechos foram remissão de sintomas, imagem corporal, distorção cognitiva, comorbidade psiquiátrica, funcionamento psicossocial e satisfação do paciente. A abordagem cognitivo-comportamental foi o tratamento mais efetivo, principalmente para bulimia nervosa, transtorno da compulsão alimentar periódica e síndrome do comer noturno. Para anorexia nervosa, a abordagem familiar demonstrou maior efetividade. Outras abordagens efetivas foram psicoterapia interpessoal, terapia comportamental dialética, terapia de apoio e manuais de autoajuda. Além disso, houve um número crescente de abordagens preventivas e promocionais que contemplaram fatores de risco individuais, familiares e sociais, sendo promissoras para o desenvolvimento da autoimagem positiva e autoeficácia. São necessários mais estudos que avaliem o impacto de abordagens multidisciplinares em todos transtornos alimentares, além da relação custo-efetividade de algumas modalidades efetivas, como a terapia cognitivo-comportamental.


Assuntos
Terapia Cognitivo-Comportamental/métodos , Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/psicologia , Transtorno da Compulsão Alimentar/terapia , Medicina Baseada em Evidências , Transtornos da Alimentação e da Ingestão de Alimentos/prevenção & controle , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Humanos , Metanálise como Assunto , Ensaios Clínicos Controlados Aleatórios como Assunto , Literatura de Revisão como Assunto , Resultado do Tratamento
18.
Rev Med Suisse ; 12(522): 1141-3, 2016 Jun 08.
Artigo em Francês | MEDLINE | ID: mdl-27451514

RESUMO

At the doctor's office primary care, symptomatology of young is often vague or nonspecific. Faced with such symptoms, via the analysis of a clinical case, significant in many clinical situations, we show the importance of considering the significant members of the entourage and invite them to the surgery. A therapeutic alliance better weaves between the youth and his doctor if the environment is taken into account and will lead to better therapeutic response.


Assuntos
Comportamento do Adolescente , Transtorno da Compulsão Alimentar , Obesidade , Visita a Consultório Médico , Relações Pais-Filho , Relações Médico-Paciente , Atenção Primária à Saúde , Adolescente , Comportamento do Adolescente/psicologia , Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/psicologia , Índice de Massa Corporal , Feminino , Humanos , Obesidade/prevenção & controle , Obesidade/psicologia
19.
Appetite ; 105: 266-73, 2016 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-27263069

RESUMO

OBJECTIVE: To examine whether previously identified childhood risk factors for bulimia or compulsive eating (BCE) predict self-reported lifetime BCE by age 30 years in a prospective birth cohort. METHOD: Using data from the 1970 British Cohort Study at birth, 5, and 10 years, associations between 22 putative childhood risk factors and self-reported lifetime BCE at 30 years were examined, adjusting for sex and socioeconomic status. RESULTS: Only female sex (odds ratio (OR): 9.2; 95% confidence interval (CI): 1.9-43.7; p = 0.005), low self-esteem (OR:2.9; 95%CI: 1.1-7.5; p = 0.03) and high maternal education (OR:5.4; 95%CI: 2.0-14.8; p = 0.001) were significantly associated with higher risk of BCE, whereas high SES at 10 years was significantly protective (OR:0.2; 95%CI: 0.1-0.8; p = 0.022) of BCE in fully adjusted multivariable logistic regression analysis. DISCUSSION: Our findings do not support a strong role for childhood weight status and eating behaviours in the development of bulimia and compulsive eating pathology, rather suggesting a focus on self esteem may have greater relative importance. Findings in relation to maternal education and SES need further exploration.


Assuntos
Transtorno da Compulsão Alimentar/etiologia , Bulimia Nervosa/etiologia , Fenômenos Fisiológicos da Nutrição Infantil , Comportamento Compulsivo/etiologia , Comportamento Alimentar , Sobrepeso/prevenção & controle , Obesidade Pediátrica/fisiopatologia , Adulto , Transtorno da Compulsão Alimentar/epidemiologia , Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/psicologia , Bulimia Nervosa/epidemiologia , Bulimia Nervosa/prevenção & controle , Bulimia Nervosa/psicologia , Criança , Estudos de Coortes , Comportamento Compulsivo/epidemiologia , Comportamento Compulsivo/prevenção & controle , Comportamento Compulsivo/psicologia , Escolaridade , Comportamento Alimentar/psicologia , Feminino , Humanos , Estudos Longitudinais , Masculino , Mães/educação , Sobrepeso/epidemiologia , Sobrepeso/psicologia , Obesidade Pediátrica/psicologia , Prevalência , Estudos Prospectivos , Fatores de Risco , Autoimagem , Autorrelato , Fatores Sexuais , Reino Unido/epidemiologia
20.
Psychotherapy (Chic) ; 53(2): 188-94, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27267503

RESUMO

This article presents a brief case study of "Jane Doe," a 13-year-old, non-Hispanic White girl 2 participating in a clinical research trial of interpersonal psychotherapy-weight gain (IPT-WG). Girls at-risk for adult obesity and binge eating disorder (BED) were randomly assigned to take part in 12 weeks of preventative group treatment. Jane's IPT-WG group included five other early adolescent girls (mostly aged 12-13) at risk for adult obesity and BED. The case of Jane illustrates a successful example of IPT-WG for the prevention of excessive weight gain and for the prevention of BED. (PsycINFO Database Record


Assuntos
Transtorno da Compulsão Alimentar/prevenção & controle , Transtorno da Compulsão Alimentar/psicologia , Relações Interpessoais , Sobrepeso/prevenção & controle , Sobrepeso/psicologia , Psicoterapia Breve/métodos , Psicoterapia de Grupo/métodos , Aumento de Peso , Adolescente , Imagem Corporal , Criança , Terapia Combinada , Comunicação , Feminino , Seguimentos , Humanos , Relações Mãe-Filho , Negociação
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